South Africa began the fourth day of the second Take a look at on 15 for one – a deficit of 371 runs – after Australia declared on 575.
However the Proteas have been dismissed for simply 204 – with off-spinner Nathan Lyon taking three for 58 – as Australia raced to victory by an innings and 182 runs.
Temba Bavuma’s 65 was the one resistance of word earlier than he perished to an unpleasant slog-sweep at Lyon.
Australia’s seventh win from 11 Exams in 2022 sees them open up an unassailable 2-0 lead over the Proteas.
The hosts’ complete win hardly ever regarded doubtful after David Warner marked his one hundredth Take a look at by hitting a memorable 200.
Warner, 36, was awarded the participant of the match for his first three-figure Take a look at return since January 2020.
The concluding match of the three-Take a look at sequence begins in Sydney on January 3.
Further reporting from PA